Yes, ActiveCapture can also be used with non-GenICam cameras.
In this case, the software and frame grabber cannot communicate directly to the camera and you need to collect the camera values manually. The frame grabber requires information on the resolution, bit depth and tap mode of the camera. These values can be found in the camera manuals provided by the camera manufacturer.
We recommend saving these values in a configuration file (.pcf). The information then becomes quickly accessible by simply uploading the .pcf file into ActiveCapture any time needed. See this tutorial video to learn how to set up a .pcf file and how the setup works within ActiveCapture.